Boston University Superfund Research Program

BU SBRP researcher Jennifer Schlezinger (Project 4) recently published a paper titled "An L-Tyrosine Derivative and PPAR Gamma Agonist, GW7845, Activates a Multifaceted Caspase Cascade in Bone Marrow B Cells" in the journal Toxicological Sciences. In this experiment Schlezinger et al. examined the molecular mechanisms of cell death for the drug GW7845 to investigate how PPAR gamma agonists may contribute to tumor killing as well as normal bone marrow B lymphocyte toxicity.