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Boston University Superfund Research Program

 
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News and Updates

New book chapter from Projects 5 and 6

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BU SBRP researchers John Stegeman (Project 6) and Mark Hahn (Project 5) with Christopher Reddy of the Woods Hole Oceanographic Institution have coauthored a book chapter in Oceans and Human Health: Risks and Remedies from the Seas. The chapter is titled “Organic Pollutants: Presence and Effects in Humans and Marine Animals.” Drawing on their SBRP research and extensive experience in the field, Dr. Stegeman and Dr. Hahn review the processes and trends in the distribution of organic chemicals in the oceans, including both man-made and naturally produced chemicals, and some of the mechanisms by which these contaminants cause toxicity. They also discuss the process and extent to which such knowledge can be extrapolated to predict the impact of these compounds on humans and marine animals, including animals inhabiting marine Superfund sites.
 

Two new publications from Project 3

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Two papers by BU SBRP researcher Dr. David Waxman were recently published.  These papers, based on Dr. Waxman’s work in Project 3, are “The induction of atherogenic dyslipidaemia in poloxamer 407-treated mice is not mediated through PPARα” in the Journal of Pharmacy and Pharmacology and “Circulating free fatty acids are increased independently of PPARγ activity after administration of poloxamer 407 to mice” in the Canadian Journal of Physiology and Pharmacology.

Poloxamer 407 is a surface acting agent found in cosmetics, contact lens solution, toothpaste, and mouthwash. These papers provide insight into whether PPARs, a group of nuclear receptor proteins that act as transcription factors, have a role in the modulation of lipid levels in blood after administration of poloxamer 407.


Last Updated ( Thursday, 02 October 2008 14:10 )
 

New Research Translation and Community Outreach staff

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Gregory Patts has joined the Research Translation and Community Outreach staff at BU SBRP. At Population Services International in Washington D.C., Gregory gained web administration and public health research experience. Gregory is an MPH student at BU School of Public Health and can be This e-mail address is being protected from spambots, you need JavaScript enabled to view it for information regarding the Research Translation and Community Outreach cores.

Raphael Adamek, who for two years played an instrumental and persistently creative role in Research Translation and Community Outreach, is leaving BU SBRP to attend Harvard as a full-time student. He will pursue a Masters of Education degree with a focus on Education Policy and Management. While Raph plans to stay involved in Research Translation and Community Outreach projects, the bulk of Raph’s responsibilities will be passed to Gregory.

Last Updated ( Wednesday, 03 September 2008 10:20 )
 

New publication from projects 1 and 2 in the International Journal of Health Geographics

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BU SBRP researchers Dr. Veronica Vieira (Project 2), Dr. Tom Webster (Project 2), and Dr. Ann Aschengrau (Project 1) recently published a paper titled “Spatial-temporal analysis of breast cancer in upper Cape Cod, Massachusetts” in the International Journal of Health Geographics. In this paper the researchers examined the association between participants' residential history during 1947-1993 and the risk of breast cancer diagnosis during 1983-1993 using generalized additive models (GAMs). The models included a two-dimensional space only analysis, one-dimensional time analyses for the earliest year study participants lived in the study area and the residency duration, a two-dimensional time-only analysis, and a two dimensional analysis for space and time.

The results of these analyses showed a number of statistically significant relationships between time, space, and the development of breast cancer. These results show that GAM methods are a suitable alternative to widely-used cluster detection methods and may be preferable when residential histories from existing epidemiological studies are available.

The International Journal of Health Geographics is an Open Access Journal, so a full copy of this article is available for free online.

 

Scammell to help review Glendale Road Landfill cancer study

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Dr. Madeleine Scammell, PI of the Community Outreach Core, is one of three experts who have volunteered to review a cancer study of residents surrounding the Glendale Road Landfill in Northhampton, Massachusetts. This cancer study, conducted by the Gradient Corporation, examined the cancer rates for 18 types of cancer and concluded that none of these rates were statistically higher in the residents living near the Glendale Road Landfill when compared to the state average.  Members of Citizens United for a Healthy Future reached a different conclusion from the study, arguing that the study shows a significantly higher rate of total female cancer within a mile of the landfill when compared to the state average.

Scammell, Dr. Richard Clapp, and Molly Jacobs will review the data from the Gradient study and present their results next month.

 


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